In 1952, the Highway Bureau divided supervision from transportation business, and established Kaohsiung Motor Vehicles Office, which was renamed the 5th District Motor Vehicles Office of Highway Bureau in 1966, followed by the establishment of four stations – Pingtung, Taitung, Penghu, and Cishan within its jurisdiction. Taitung Station was thus established. On July 1, 1999, it became an affiliate under the jurisdiction of the subordinates of the Ministry of Transportation and Communications, pursuant to the Provisional Regulations for Each Motor Vehicles Office, Highway Bureau of Ministry of Transportation and Communications stipulated in Article 11 of the Provisional Regulations of Highway Bureau, Ministry of Transportation and Communications in the 2nd Paragraph, Article 5 of the Provisional Statute for the Reorganization of Taiwan Provincial Government. Furthermore, for the legalization of government organizations, the Organic Act for Each Motor Vehicles Office, Directorate General of Highways, Ministry of Transportation and Communications was enacted by the President on January 21, 2002 after it was approved in the third reading of the Legislative Yuan, and then was put into effect since January 30, 2002 with the approval of the Executive Yuan in the document of Yuan-Tai-Wun-Zih No. 0910004320-A dated January 29, 2002. In the meantime, Taitung Station was renamed Taitung Station, Kaohsiung Motor Vehicles Office, Directorate General of Highways of Ministry of Transportation and Communications.

        Taitung Station was temporarily located at the guildhall of the Fuzhou fellow townsmen association at the initial stage of its establishment, and then moved to No. 268 on Sinsheng Road. In the beginning of 1976, the new building at No. 441, Jhengci N. Road was constructed, and the staff and facility of Taitung Station moved into the new building in July of the same year. Taitung Station has run its business on this new location since then. There were only 8 staffs upon the establishment of Taitung Station. With the increase of business volume, the First and Second Subsections were established in 1981, and the Third and Fourth Subsections were established in 1993, in order to take charge of different duties. In 1999, the Fifth Subsection was set up to respond to police offense cases transferred to motor vehicle offices and correction of the organization, and the staff increased to 42 persons. The five subsections reduced to four in accordance with the policy in the end of 2002. To respond to the growth of business volume, computerized management was implemented in 1984. The Highway Bureau established its computer centers in northern, central and southern Taiwan, and Taitung Station also set up the computer room in 1993 to perform the business. On February 28, 1994, the first-generation operating system was upgraded to second-generation computer system, of which new functions were added, and national network was established, in order to expand the objectives of citizen service.